It is set during the Clone Wars animated series, as well as certain scenes from Star Wars: Episode II – Attack of the Clones, unlike the original games, which featured characters from the six films of Star Wars such as Lego Star Wars: The Video Game and Lego Star Wars II: The Original Trilogy.
Also, the space fights have been remodelled to use a more instinctive, 3D-space battle sensation.
The game also features some real-time strategy elements, such as commanding large ground armies across battlefields. It introduces a few novelties, including scene swap, where players can switch between teams in separate locations to complete multi-part objectives, and boss battles. Up to two players can switch between different characters to fight enemies in combat, solve puzzles, and progress through various levels. Gameplay in Lego Star Wars III: The Clone Wars is similar to the previous titles in the series, and other Lego video games.